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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
25.76
Human Site:
S281
Identified Species:
47.22
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S281
S
P
F
G
Q
P
F
S
Q
A
G
G
Q
P
M
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S281
S
P
F
G
Q
P
F
S
Q
A
G
G
Q
P
M
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S281
S
P
F
G
Q
P
F
S
Q
A
G
G
Q
P
M
Dog
Lupus familis
XP_851777
2404
260682
S281
S
P
F
G
Q
P
F
S
Q
T
G
G
Q
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S280
S
P
F
G
Q
P
F
S
Q
T
G
G
Q
Q
M
Rat
Rattus norvegicus
NP_596872
2444
265618
S280
S
P
F
G
Q
P
F
S
Q
T
G
G
Q
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
S267
S
P
F
G
Q
P
F
S
Q
T
G
G
Q
Q
M
Frog
Xenopus laevis
NP_001088637
2428
264402
N274
S
P
F
G
Q
T
F
N
Q
A
A
G
Q
Q
I
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
S203
Q
T
A
P
A
L
P
S
S
T
P
I
D
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
A371
Q
Q
Q
Q
Q
L
L
A
Q
Q
M
A
Q
R
G
Honey Bee
Apis mellifera
XP_001122031
2606
284119
Q287
A
V
T
M
Q
Q
Q
Q
Q
A
H
M
V
G
P
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
G148
M
M
S
P
P
S
M
G
R
V
P
G
P
S
P
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
P351
T
Q
S
N
T
N
N
P
F
H
G
F
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
N.A.
86.6
66.6
13.3
N.A.
20
20
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
N.A.
86.6
80
13.3
N.A.
26.6
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
0
8
0
39
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
62
0
0
0
62
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
62
0
0
0
8
0
0
62
70
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% L
% Met:
8
8
0
8
0
0
8
0
0
0
8
8
0
0
54
% M
% Asn:
0
0
0
8
0
8
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
62
0
16
8
54
8
8
0
0
16
0
8
39
16
% P
% Gln:
16
16
8
8
77
8
8
8
77
8
0
0
70
31
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
62
0
16
0
0
8
0
62
8
0
0
0
8
16
16
% S
% Thr:
8
8
8
0
8
8
0
0
0
39
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _